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September 27, 2025International Journal of Molecular SciencesOpen Access

Rewinding the Clock: Emerging Pharmacological Strategies for Human Anti-Aging Therapy

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Authors

CDCharlotte DelrueRSReinhart SpeeckaertMSMarijn M. Speeckaert

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Overview

This review highlights pharmacotherapeutic interventions and challenges in targeting aging, suggesting new approaches for enhancing healthspan.

Key Points

  • Aging is marked by physiological decline and increased disease vulnerability, impacting overall health.
  • Emerging pharmacotherapeutic strategies include senolytics and NAD+ precursors, showing promise in recent trials.
  • Reviewing the evidence and mechanisms behind these therapies is crucial for their application to clinical contexts.
  • Identifying biomarkers and addressing safety and regulatory challenges are key for advancing these therapies.

Cite This Study

Delrue et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3e2eebfec0fc5236beahttps://doi.org/10.3390/ijms26199372
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review2026 · 7 citations
  2. 2Insights into the therapeutic strategies for aging and aging-associated diseases2026 · 4 citations
  3. 3Pharmacological approaches to anti-age therapy2025
  4. 4Recent progress in stem cell and immune cell-based interventions for aging and age-related disorders2025
  5. 5Emerging biological therapies for healthy aging: targeting inflammaging, senescence, and regenerative decline2026