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September 27, 2025European Journal of PainOpen Access

Altered Topology of Brain Structural Network in Patients With Migraine Without Aura: A Structural MRI Study

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Authors

ZCZimin CaoJJJing‐Nan JiaGLGuoyun Liu

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Overview

Study reveals altered brain network structure in migraine patients, suggesting a distinct neurovascular disease pathology.

Key Points

  • Migraine patients show altered topological organization of brain networks, indicating possible pathophysiological insights.
  • Significant differences were found in anxiety and depression scores between migraine patients and healthy controls.
  • Graph theoretical analysis was utilized to assess global and regional structural network properties in the brain.
  • Findings may provide new perspectives on migraine diagnosis and treatment.
  • The study identifies specific brain regions with magnified changes related to connectivity.

Cite This Study

Cao et al. (2025) studied this question.

synapsesocial.com/papers/68d7be5eeebfec0fc52375d1https://doi.org/10.1002/ejp.70129
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