Retrospective study finds TP53 mutations influence prognosis in acute leukemia patients, highlighting the need for further exploration.
Background Acute leukemia with gene mutations, particularly TP53, is associated with poor prognosis, yet their impact in middle-aged and elderly patients remains insufficiently explored. This study evaluated the prevalence and prognostic significance of TP53 mutations in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL).
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Peng et al. (2025) studied this question.
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