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September 27, 2025Open Access

Sources of outdoor air pollution exposure and child brain network development across the United States

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Authors

KBKatherine L. BottenhornKSKirthana SukumaranJCJordan D. Corbett

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Overview

Longitudinal analysis links PM2.5 exposure to brain network changes in children, suggesting neurotoxic effects.

Key Points

  • Childhood exposure to PM2.5 from traffic emissions impacted brain network connectivity, indicating potential neurotoxic risks.
  • Findings reveal that PM2.5 exposure is linked to varying patterns of brain connectivity, specifically impacting higher-order cognition.
  • Examination using predictive modeling assessed differences in functional brain network connectivity across a wide U.S. sample.
  • Results highlight regional disparities in neurotoxic effects, particularly among youth in the northeastern United States.

Cite This Study

Bottenhorn et al. (2025) studied this question.

synapsesocial.com/papers/68d7be66eebfec0fc5237e1chttps://doi.org/10.1101/2025.09.23.677862
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