Case report describes atypical imaging features of epithelioid hemangioendothelioma, suggesting further awareness. Liver biopsy confirmed diagnosis in a 65-year-old woman.
Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor that can affect various organs. This report describes a 65-year-old woman who presented with abdominal pain, weight loss, and elevated liver enzymes. After the diagnostic workup, a percutaneous biopsy of the liver lesions showed histological changes in EHE. What stands out in this case is that imaging studies revealed multiple cystic lesions with fluid-fluid levels, even though such manifestation is not typically seen in this disease. This case emphasizes the importance of considering EHE in the differential diagnosis of hepatic lesions, even in atypical presentations.
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Rezvan et al. (2025) studied this question.
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