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September 28, 2025Analytical Chemistry

Electrochemical Platform Regulated by Cyclodextrin Chiral Microenvironments for Enhanced Enantioselective Recognition

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Authors

TSTiantian SuMYMei YangSWShujia Wang

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Overview

This electrochemical platform enables enhanced enantioselective recognition using cyclodextrin microenvironments, highlighting its implications for drug safety.

Key Points

  • The platform significantly improves enantioselective recognition, allowing precise monitoring of enantiomers in real-time.
  • Using l- and d-histidine, this system demonstrates enhanced discrimination with distinct interactions observed through molecular docking.
  • Constructed with l-tryptophan-functionalized cyclodextrin, this electrochemical setup integrates sustainable materials for efficient analysis.
  • The findings indicate potential applications in pharmaceuticals and biomedicine, supporting the need for improved chiral discrimination methods.

Cite This Study

Su et al. (2025) studied this question.

synapsesocial.com/papers/68d90a0141e1c178a14f5ec6https://doi.org/10.1021/acs.analchem.5c04392
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