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Interrelationship Between Cardiopulmonary Exercise Testing Indices and Markers of Subclinical Cardiovascular Dysfunction in Those with Type 2 Diabetes—An Observational Cross-Sectional Analysis

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Observational analysis shows CPET indices are impaired in those with type 2 diabetes, suggesting potential risks.

CPET indices indicate a significant impairment in exercise tolerance among participants with type 2 diabetes.
All measured CPET outcomes were lower in individuals with type 2 diabetes compared to healthy controls.
Multiple linear regression identified specific CPET outcomes associated with cardiovascular markers in type 2 diabetes.
These CPET indices may help predict individuals at greater risk of developing symptomatic heart failure.

Walters et al. (2025) studied this question.

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