Green Synthesis Characterization and Antimicrobial Activity of Complex of Amide Ligand with Ni(II)

The present research describes the synthesis, spectroscopic characterization, and antibacterial investigations of several Nickle (II) complexes with pyrimidine derivatives. The compounds were characterized using magnetic susceptibility measurements, infrared spectroscopy, electronic spectroscopy, and elemental analysis. Both the ligands and their complexes exhibited antibacterial activity against the pathogens Staphylococcus aureus and Escherichia coli. The diffuse reflectance spectra showed characteristic bands corresponding to the electronic transitions, consistent with an octahedral geometry around the Ni (II) ion. The observed magnetic moment further supports the high-spin octahedral environment. Overall, the synthetic approach has been found to be simpler, practical, and environmentally.