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Case report details a 26-year-old woman with myocardial infarction and comorbidities, suggesting critical need for early risk assessment and intervention.
Acute coronary syndrome (ACS) in young females is uncommon. The presence of different comorbidities like hypertension, diabetes, and dyslipidemia increases the risk of ACS. Adverse outcomes can be prevented by having early recognition and intervention. A 26-year-old female with a history of hypertension, diabetes mellitus, and dyslipidemia presented with initially intermittent left-sided chest pain radiating to the jaw but progressive in the last five days and associated with left arm numbness. Her ECG showed anteroseptal T-wave inversion, and her troponin level was also elevated. Echocardiography revealed anteroseptal hypokinesia with an ejection fraction of 45%. The diagnosis was made of non-ST-elevation myocardial infarction. Additionally, on coronary angiography, stenosis of the proximal to mid-left anterior descending (LAD) artery was shown, for which she underwent successful percutaneous transluminal coronary angioplasty and drug-eluting stent of the proximal LAD artery. This case shows the importance of early cardiovascular risk screening and intervention, even in the absence of traditional risk factors like smoking. Furthermore, it shows an increasing incidence of premature coronary artery disease in young females with a history of comorbidities like hypertension, diabetes mellitus, and dyslipidemia.
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Sharma et al. (2025) studied this question.
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