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September 30, 2025Current OncologyOpen Access

The Role of LncRNAs in Radio- and Chemoresistance of Glioblastoma: Prognostic or Therapeutic?

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Authors

ETElisa TremanteAMAna Belén Díaz MéndezMRMaria Giulia Rizzo

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Overview

This review highlights lncRNAs' role in glioblastoma therapy resistance, suggesting therapeutic implications and prognostic value.

Key Points

  • LncRNAs significantly influence therapy resistance in glioblastoma, affecting prognosis and treatment outcomes.
  • Current research emphasizes lncRNAs' potential as biomarkers and therapeutic targets in malignant brain tumors.
  • Impaired expression of lncRNAs in glioblastoma contributes to altered cellular processes, including proliferation and metastasis.
  • Investigating lncRNAs' specific roles in therapy resistance may lead to improved treatment strategies and diagnostics.

Cite This Study

Tremante et al. (2025) studied this question.

synapsesocial.com/papers/68dc1e438a7d58c25ebb230chttps://doi.org/10.3390/curroncol32100539
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Unraveling the Function of lncRNAs in Gliomas: Interaction With Signaling Pathways and Therapeutic Opportunities2026
  2. 2The Potential Roles and Applications of the long non-coding RNA- Interactome in glioblastoma Etiology and Treatment2025 · 1 citations
  3. 3Role of non-coding RNAs in radiotherapy sensitivity in non-small cell lung cancer2025
  4. 4Role of non-coding RNAs in radiotherapy sensitivity in non-small cell lung cancer2025
  5. 5Functional Roles of Long Non-coding RNAs on Stem Cell-related Pathways in Glioblastoma2024