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September 30, 2025Frontiers in NutritionOpen Access

Intermittent enteral nutrition may increase gastrointestinal complications and mortality in critically ill patients

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Authors

PHPing HuHWHaopeng WuKZKai Zhang

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Overview

Meta-analysis compares intermittent enteral nutrition with continuous enteral nutrition in ICU patients, suggesting higher complications.

Key Points

  • Intermittent enteral nutrition is linked to greater gastrointestinal complications and higher ICU mortality.
  • Patients receiving intermittent enteral nutrition showed an increased risk of diarrhea and abdominal distension compared to continuous enteral nutrition.
  • Randomized controlled trials were analyzed, showing that continuous enteral nutrition is more effective for critically ill patients requiring mechanical ventilation.
  • These findings underscore the importance of tailored nutritional strategies in managing critically ill patients' care.

Cite This Study

Hu et al. (2025) studied this question.

synapsesocial.com/papers/68dc262a8a7d58c25ebb351fhttps://doi.org/10.3389/fnut.2025.1667836
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Enteral nutrition interruption in critically ill patients: a systematic review and meta-analysis of prevalence, causes, and clinical outcomes2026
  2. 2Effects of enteral nutrition initiation time and nutritional adequacy on the prognosis of critically ill adults: systematic review and meta-analysis2026
  3. 3Energy-dense versus routine enteral nutrition in critically ill patients: a systematic review and meta-analysis2025
  4. 4Interruptions of enteral nutrition in intensive care units: mechanisms, clinical impacts, and precision nursing interventions–a scoping review2026
  5. 5Clinical and metabolic phenotyping of continuous versus intermittent ENteral NUTrition in ventilated adults with shock: ENNUT trial protocol2025