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September 30, 2025International Journal of Research in Medical SciencesOpen Access

Links between vitamin D receptor gene polymorphisms and coronary artery disease: a review of evidence

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Authors

MMM. Maruf-Ur-RahmanMIMd. Rafiqul IslamWBWajeeha Begum

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Overview

This review highlights the connection between vitamin D receptor gene polymorphisms and coronary artery disease, suggesting significant implications for genetic risk assessment.

Key Points

  • Genetic variants in the vitamin D receptor gene are potentially linked to a higher risk of coronary artery disease.
  • Four specific polymorphisms—FokI, ApaI, BsmI, and TaqI—are extensively studied for their association with coronary artery disease.
  • Variability in findings across different populations highlights the need for further investigation into these genetic correlations.
  • This review synthesizes existing literature on the relationship between vitamin D receptor gene polymorphisms and coronary artery disease.

Cite This Study

Maruf-Ur-Rahman et al. (2025) studied this question.

synapsesocial.com/papers/68dc262a8a7d58c25ebb366dhttps://doi.org/10.18203/2320-6012.ijrms20253208
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Relationship between vitamin D deficiency, vitamin D receptor gene variants, and the risk of coronary artery disease among South Indians: A case-control study2025
  2. 2Associations of VDR gene polymorphisms and haplotypes with dental caries: a systematic review and meta-analysis2026
  3. 3The Association of Vitamin D Receptor Polymorphisms with COVID-19 Severity2024 · 6 citations
  4. 4Association of VDR gene polymorphisms with prediabetes and Type 2 diabetes mellitus in a sample of the Iranian population2026
  5. 5Study of Association of Vitamin D Receptor Gene Polymorphisms with Diabetic Nephropathy2024 · 3 citations