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September 30, 2025International Journal of Research in Medical SciencesOpen Access

Effects of probiotics on neurodegenerative diseases

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Authors

JCJesús CórdovaEFEdison H. FreilePAPrisca del P. Acosta

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Overview

Clinical and preclinical evidence suggests probiotics can reduce inflammation in Alzheimer's and Parkinson's diseases, implying potential therapeutic roles.

Key Points

  • Probiotics are linked to improved cognitive functions in Alzheimer's disease and reduction of inflammatory markers.
  • In Parkinson's disease, strains like Lactobacillus and Bifidobacterium have shown benefits for gastrointestinal symptoms and inflammation.
  • Research indicates probiotics modulate neuroinflammation and oxidative stress, suggesting mechanisms of neuroprotection.
  • Current studies show variability in strain effects and study designs, calling for standardized protocols for future research.

Cite This Study

Córdova et al. (2025) studied this question.

synapsesocial.com/papers/68dc262a8a7d58c25ebb3675https://doi.org/10.18203/2320-6012.ijrms20253209
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Gut Microbiota Modulation with Probiotics: Potential Therapeutic Avenues for Alzheimer’s and Parkinson’s Diseases2025 · 2 citations
  2. 2Unveiling the Therapeutic Potential of Modern Probiotics in Addressing Neurodegenerative Disorders: A Comprehensive Exploration, Review and Future Perspectives on Intervention Strategies2024 · 20 citations
  3. 3From Gut to Brain: Targeting Probiotics in Neurodegenerative Health2024
  4. 4Impact of the gut–brain axis on neurodegenerative diseases and potential benefits of probiotics2024 · 1 citations
  5. 5Translational Perspectives on Anti-Inflammatory Interventions for Neurodegenerative Disorders: Evidence from Gut-Brain Axis2026