Case report details recurrent uveitis due to latent tuberculosis in a patient with psoriatic spondyloarthropathy, highlighting diagnostic challenges.
Uveitis is a multifactorial intraocular inflammatory disorder that may arise from autoimmune, infectious, or idiopathic causes, often presenting diagnostic and therapeutic challenges when overlapping etiologies coexist. This report describes a 35-year-old male with psoriatic spondyloarthropathy and newly diagnosed latent tuberculosis, who experienced recurrent episodes of ocular redness, photophobia, and blurred vision for over a decade. Examination revealed anterior chamber inflammation with posterior synechiae and mild vitreous spillover. Interferongamma release assay (Quantiferon-TB Gold) was positive, confirming latent tuberculosis. Treatment with topical corticosteroids, cycloplegics, and isoniazid led to favorable visual and symptomatic outcomes. The case highlights the need for comprehensive systemic evaluation in patients presenting with recurrent uveitis to differentiate between autoimmune and infectious triggers
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Pradeep et al. (2025) studied this question.
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