One Case of Acute Syphilitic Posterior Placoid Chorioretinitis Complicated by Tuberculosis Infection

Abstract Objective: This study presents a case of acute syphilitic posterior placoid chorioretinitis (ASPPC) complicated by Tuberculosis Infection. Case Description: An individual initially diagnosed with tuberculous chorioretinitis received quadruple anti-tuberculosis therapy in conjunction with glucocorticoid medications for a 4-month period. However, the condition deteriorated abruptly following an initial improvement. Subsequent systemic assessment revealed a positive syphilis diagnosis. Following 1 month of penicillin treatment, significant improvement was observed, and the patient maintained stability throughout the 4-year follow-up period. Conclusions: This case highlights the importance of considering the potential for dual or multiple infections in the diagnostic evaluation of uveitis.