How High-Flow Nasal Cannula Is Impacted by Nasogastric/Esophageal Tube: A Bench Study

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Bench study evaluates how nasal tube placement affects dead space clearance and airway resistance.

Standard cannulas have minimal effects when paired with smaller nasogastric tubes, maintaining performance.
Larger tubes (12-Fr, 16-Fr) increase airway pressure and decrease CO2 clearance, potentially complicating treatment.
Asymmetrical cannulas demonstrate varying effects based on tube side placement, affecting effectiveness.
Excessive nares occlusion may necessitate downsizing the cannula to optimize respiratory therapy.

Vieira et al. (2025) studied this question.

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