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October 1, 2025MedicineOpen Access

Association of immune cells with the risk of basal cell carcinoma: A bidirectional Mendelian randomized study

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Authors

SWSuyao WangYLYuying LiSHShaolei Huang

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Overview

Bidirectional mendelian randomization reveals causal associations between immune cells and basal cell carcinoma, suggesting potential intervention targets.

Key Points

  • Bidirectional analysis highlighted 14 immune phenotypes causally associated with basal cell carcinoma.
  • Two immune phenotypes remained significant after correction for multiple testing, one acting as a risk factor and the other as a protective factor.
  • The study utilized mendelian randomization to assess the relationships using data from over 731 immune cell phenotypes.
  • Findings suggest potential pathways for early identification and intervention in basal cell carcinoma.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68dd91d5fe798ba2fc4990b2https://doi.org/10.1097/md.0000000000044656
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