Analysis of Genomic and Transcriptomic Data Revealed Key Genes and Processes in the Development of Major Depressive Disorder

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Transcriptome-wide association study identified crucial genes and pathways in major depressive disorder, indicating sex-specific effects.

Identifying key genes and pathways contributes to understanding major depressive disorder development.
The study highlighted sex-specific gene expression changes associated with major depressive disorder risk.
A transcriptome-wide association study revealed significant alterations in gene transcription linked to major depressive disorder.
Pathway enrichment analysis elucidated processes like neurotransmitter metabolism and chromatin remodeling related to major depressive disorder.

Ivanov et al. (2025) studied this question.

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