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Case analysis reveals optimal strategies for addressing metabolic complications in splenic trauma, highlighting MODS.
The surgical and medical management of organ damage and metabolic complications following high-energy multi-trauma presents a significant clinical challenge. Factors such as severe physiological stress, sympathetic nervous system activation, blood and fluid loss, elevated intracranial pressure, and systemic inflammation can precipitate profound metabolic disturbances, leading to liver and kidney dysfunction, as well as cardiac cell injury, even in the absence of direct trauma to these organs. Despite successful bleeding control and aggressive fluid and electrolyte resuscitation, patients may enter a vicious cycle of metabolic deterioration. Cardiac dysfunction and arrhythmias can develop rapidly, often culminating in sudden death. Early recognition of the pathophysiological mechanisms underlying clinical deterioration and timely intervention are crucial to improving survival. This study analyzes the literature and presents a case-based discussion to explore optimal strategies for managing metabolic complications associated with isolated splenic lacerations resulting from high-energy trauma, with a particular focus on the development of Multiple Organ Dysfunction Syndrome (MODS).
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Benibol et al. (2025) studied this question.
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