Mechanisms of Natural and Adaptative Immunity in Infections Associated With Herpes Simplex of Types 1 and 2

Herpes infection is one of the most common infections, having chronic course with frequent long exacerbations and high resistance to the therapy. Recurrent herpetic infection is a type of infection with constant persistence of the pathogen. However, the clinical manifestation of the infection, recurrence and progression of the disease is determined not only by the efficient functioning of specific antiviral immunity, but also by general reactivity of a macroorganism. The article considers the important sides of the innate and adaptive immunity, mechanisms to avoid viruses from immune factors, discusses the important role of laboratory examination in monitoring the state of patients with recurrent herpes infection.