Integrating harm reduction and addiction care in HIV prevention among persons who inject drugs in the United States—a narrative review

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Narrative review highlights barriers to PrEP uptake in persons who inject drugs, suggesting integrated care models.

The trend of new HIV cases related to injection drug use has significantly increased, indicating a need for intervention.
Low uptake of preexposure prophylaxis is observed among persons who inject drugs, despite its proven efficacy to prevent HIV.
Integrating addiction care with HIV prevention strategies could address multilevel barriers for persons who inject drugs.
Policies and funding for syringe services programs and opioid treatment programs are crucial for effective HIV prevention.

Wei-Teng Yang (2025) studied this question.

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