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October 1, 2025

Figure S1 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice

Shweta Tiwary Kevin S. Hsu Katherine C. Goldfarbmuren Zheng Xia Jay A. Berzofsky

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Key Points

DHA significantly enhances dendritic cell function, leading to improved cancer vaccine responses.
Measurements indicated higher serum DHA levels in FAT-1 mice compared to WT mice, confirming effective fatty acid conversion.
Assessment using ELISA on serum samples demonstrated distinct differences in omega-3 fatty acid levels.
These findings highlight the potential role of dietary fatty acids in cancer immunotherapy strategies.

Implication

Analysis reveals DHA improves dendritic cell antigen presentation in mice, suggesting enhanced vaccine efficacy.

Abstract

Figure S1: DHA levels in FAT-1 Vs WT mouse serum. Serum was isolated from naïve FAT-1 (N = 3) and WT (N = 3) mice and DHA was measured by ELISA.

Discussion

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Cite This Study

Tiwary et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a219f6 https://doi.org/10.1158/2326-6066.30255365

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S7 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
2Figure S4 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
3Figure S9 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
4Figure S3 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
5Figure S6 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025

Figure S5 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
Figure S2 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
Figure S8 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025