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October 1, 2025Open Access

Figure S6 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice

Shweta Tiwary Kevin S. Hsu Katherine C. Goldfarbmuren Zheng Xia Jay A. Berzofsky

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Key Points

Higher percentages of activated T-cells were observed in vaccinated tumor-bearing mice compared to controls.
FAT-1 vaccinated animals had significantly more CD8+ PDL-1/PDL-2+ T-cells, indicating enhanced immune response.
Research indicates that omega-3 fatty acids may boost the efficacy of dendritic cell-based cancer vaccines.
The study highlights the role of omega-3 fatty acids in promoting dendritic cell-mediated antigen presentation.

Implication

Vaccinated mice showed increased T-cell activation, suggesting omega-3 fatty acids improve dendritic cell functions.

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Cite This Study

Tiwary et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21a0a https://doi.org/10.1158/2326-6066.30255350

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S3 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
2Figure S4 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
3Figure S5 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
4Figure S2 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
5Figure S1 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025

Figure S7 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
Figure S9 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
Figure S8 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025