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October 1, 2025Open Access

Figure S7 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice

Shweta Tiwary Kevin S. Hsu Katherine C. Goldfarbmuren Zheng Xia Jay A. Berzofsky

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Key Points

Increased levels of omega-3 fatty acids improve dendritic cell function in presenting antigens to CD8 T cells.
The study utilized varying doses of DHA, leading to enhanced efficacy of dendritic cell-based cancer vaccines.
Dendritic cells generated from WT mice exhibited improved antigen presentation capabilities with higher DHA doses.
Findings indicate that dietary omega-3 fatty acids may potentiate immune responses against cancer.

Implication

Dendritic cells enhanced antigen presentation with varying DHA levels in mice, suggesting better vaccine efficacy.

Abstract

Figure S7: Antigen presentation assay to test the ability of DCs generated from WT mice in varying doses of DHA in presenting antigen to CD8 T cells.

Discussion

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Cite This Study

Tiwary et al. (2025) studied this question.

synapsesocial.com/papers/68e040f7a99c246f578b3d43 https://doi.org/10.1158/2326-6066.30255347

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S8 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
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3Figure S3 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
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5Figure S4 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025

Figure S2 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
Figure S6 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025
Figure S5 from High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell–Based Cancer Vaccine Efficacy in Mice2025