Supplementary Figure 6 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas

This is a Quantitative Study study.

Key Points

Endoglin-directed CAR T cells effectively target tumors in advanced sarcomas with significant response.
The c-SN6j/TRC105 antibody fails to recognize murine or rhesus endoglin, affecting experimental design.
Analysis focused on tumor targeting efficacy in advanced sarcomas using endoglin-directed CAR T cells.
The findings support the potential of targeting endoglin in treating advanced sarcoma; further studies needed.

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Observational analysis shows endoglin-directed CAR T cell efficacy in targeting tumors, indicating potential for advanced sarcoma treatments.

The c-SN6j/TRC105 antibody does not recognize murine or rhesus endoglin.

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Berger et al. (2025) studied this question.

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