October 2, 2025Open Access

Supplementary figure 1 from Nrf2 Hyperactivation as a Driver of Radiotherapy Resistance and Suppressed Antitumor Immunity in Head and Neck Squamous Cell Carcinoma

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Nrf2 hyperactivation may contribute to radiotherapy resistance in cancer patients.
The study indicates that tobacco carcinogen influences primary tumor growth significantly.
Head and neck squamous cell carcinoma shows suppressed antitumor immunity linked to Nrf2 activity.
Understanding Nrf2's role could help develop better therapeutic strategies against cancer.

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Observational analysis shows Nrf2 activation drives radiotherapy resistance in head and neck tumors, suggesting effects on tumor growth.

Primary tumor growth influenced by tobacco carcinogen, BAP

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Patel et al. (2025) studied this question.

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Observational analysis shows Nrf2 activation drives radiotherapy resistance in head and neck tumors, suggesting effects on tumor growth.

Primary tumor growth influenced by tobacco carcinogen, BAP