Supplementary figure 4 from Nrf2 Hyperactivation as a Driver of Radiotherapy Resistance and Suppressed Antitumor Immunity in Head and Neck Squamous Cell Carcinoma
Key Points
Nrf2 hyperactivation contributes to radiotherapy resistance and suppresses antitumor immunity.
The role of keap1 haploinsufficiency is crucial in influencing primary tumor growth.
Findings suggest that targeting nrf2 may enhance treatment effectiveness against head and neck cancers.
The study highlights the importance of understanding tumor biology in improving therapeutic strategies.
Abstract
Primary tumor growth influenced by Keap1 haploinsufficiency