October 2, 2025Iraqi Journal of ScienceOpen Access

A Novel Oxopyrimidine and Pyrazole Derivatives: Synthesis, Characterization and Biological Activity Study

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Discussion

Novel compounds exhibit antibacterial activity against Pseudomonas and Staphylococcus aureus, highlighting potential for drug development.

Effective antibacterial activity was demonstrated by compounds 1 and 5, particularly against Staphylococcus aureus.
Synthesis involved characterizing compounds using FTIR and NMR spectroscopy, ensuring structural integrity.
Azo compounds were created from a diazonium salt reaction, serving as precursors for the target derivatives.
The study provides insight into the potential of oxopyrimidine and pyrazole derivatives for therapeutic uses.

Ali et al. (2025) studied this question.

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Novel compounds exhibit antibacterial activity against Pseudomonas and Staphylococcus aureus, highlighting potential for drug development.