This review uncovers the impact of local infections on outcomes in patients with mechanical circulatory support, highlighting biomaterials' role and antimicrobial resistance.
Key Points
Local infections significantly impair clinical outcomes in patients using ventricular assist devices, often leading to rehospitalization.
Bacterial colonization, primarily by Staphylococcus aureus and Staphylococcus epidermidis, remains a critical concern linked to device materials.
Current biomaterials lack durability in preventing infections, emphasizing the need for enhanced solutions that resist microbial adhesion.
Antimicrobial resistance is rising globally, complicating treatment options for those with infections related to mechanical circulatory support devices.