This protocol demonstrates effective germyl phosphorothiolation in alkenes, highlighting regioselectivity and functional group tolerance.
A copper‐catalyzed three‐component radical relay protocol is demonstrated for difunctionalization of electron‐withdrawing alkenes using germanium hydride and S ‐phosphorothiol to afford the germylphosphorothiolated product. This transformation reveals excellent tolerance for functional groups and occurs under mild reaction conditions, exhibiting a high level of regioselectivity. Control experiments suggest the involvement of germyl radicals in these transformations.
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Ghosh et al. (2025) studied this question.
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