Transcription factor TFEB belongs to MIT-TFE subfamily of the bHLHZIP transcription factor family. Currently, the function of transcription factor TFEB has been found to mainly regulate the biogenesis autophagosomes and lysosomes, and play an important role in biological functions including metabolism, angiogenesis, immunity, and inflammation. This paper reviews the structure physiological functions of TFEB, and provides support for further understanding the role of TFEB in disease.
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Chunyan Zhang (2025) studied this question.
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