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October 3, 2025BMC MicrobiologyOpen Access

Surveillance and characterization of carbapenem-resistant Enterobacter cloacae complex from China, 2015–2018

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Authors

KYKun YeYZYongqing ZhangXQXuemei Qiu

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Overview

Analysis reveals predominance of E. hormaechei within carbapenem-resistant Enterobacter cloacae, indicating significant resistance genes.

Key Points

  • Among 91 CREC isolates, 75 were identified as E. hormaechei, indicating its prevalence in clinical settings.
  • Testing revealed that 60 isolates produced carbapenemase, with blaNDM-1 being the most common resistance gene found.
  • Resistance mechanisms included both carbapenemase production and efflux pump activity in NCP isolates.
  • Results highlight significant public health concerns regarding carbapenem-resistant infections in China.

Cite This Study

Ye et al. (2025) studied this question.

synapsesocial.com/papers/68e02f34f0e39f13e7fa20bahttps://doi.org/10.1186/s12866-025-04299-4
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