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October 3, 2025Chemical CommunicationsOpen Access

Cobaltaelectro-Catalyzed C-H Acyloxylation of Aromatic and Vinylic Amide Derivatives at Room Temperature

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This method achieves regioselective C-H acyloxylation of aromatic and vinylic amides efficiently and at room temperature.
The use of 8-aminoquinoline as a directing group enhances the selectivity of the reaction.
The cobalt-catalyzed electrochemical method highlights a novel approach in organic synthesis for functionalizing amide derivatives.
This protocol presents a simplified means for achieving acyloxylation, potentially reducing both energy use and reactions times in organic chemistry.

Implication

Cobalt-catalyzed method improves C-H acyloxylation in aromatic and vinylic amides, suggesting efficiency.

Abstract

Herein, we report a mild and efficient cobalt-catalyzed electrochemical method for the regioselective C-H acyloxylation of aromatic and vinylic amides, utilizing 8-aminoquinoline as the directing group. Notably, this protocol requires...

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Cite This Study

Sitdikov et al. (2025) studied this question.

synapsesocial.com/papers/68e02f3cf0e39f13e7fa2410 https://doi.org/10.1039/d5cc04394h

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Implication

Cobalt-catalyzed method improves C-H acyloxylation in aromatic and vinylic amides, suggesting efficiency.

Cobaltaelectro-Catalyzed C-H Acyloxylation of Aromatic and Vinylic Amide Derivatives at Room Temperature

Key Points

Implication

Abstract

Discussion

Cite This Study

Cobaltaelectro-Catalyzed C-H Acyloxylation of Aromatic and Vinylic Amide Derivatives at Room Temperature

Key Points

Implication

Abstract

Discussion

Cite This Study

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