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October 3, 2025Journal of Hypertension

Triglyceride-glucose index, HOmeostatic Model Assessment index, and new-onset hypertension in middle-aged men

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Authors

LDLanfranco D’EliaDRDomenico RendinaRIRoberto Iacone

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Overview

Observational analysis reveals triglyceride-glucose index predicts new-onset hypertension in men, indicating potential as a cardiovascular risk tool.

Key Points

  • Triglyceride-glucose index was significantly associated with new-onset hypertension, highlighting its predictive value.
  • The study found TyG greater than 4.91 strongly linked to hypertension risk, unlike HOMA-IR which did not show a similar association.
  • ROC analysis identified cut-off points for TyG and HOMA-IR, underlining their different predictive capabilities.
  • Results support using TyG as a cost-effective and noninvasive tool for assessing cardiovascular risk in middle-aged men.

Cite This Study

D’Elia et al. (2025) studied this question.

synapsesocial.com/papers/68e02f3cf0e39f13e7fa27a5https://doi.org/10.1097/hjh.0000000000004162
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