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October 3, 2025Nucleic Acids ResearchOpen Access

MetaflowX: a scalable and resource-efficient workflow for multi-strategy metagenomic analysis

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Authors

YXYan XiaLLLifeng LiangXWXiaokai Wang

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Overview

Introducing MetaflowX—a workflow that enhances metagenomic analysis speed and efficiency in microbiomes.

Key Points

  • MetaflowX completed metagenomic analyses up to 14-fold faster while using 38% less disk space.
  • The framework retrieves a high number of diverse metagenome-assembled genomes (MAGs) efficiently.
  • Dedicated modules improve the quality of MAGs, boosting completeness by 5.6% and reducing contamination by 53%.
  • Functional annotation identifies critical features like virulence and antibiotic resistance genes.

Cite This Study

Xia et al. (2025) studied this question.

synapsesocial.com/papers/68e034f7f0e39f13e7fa322ahttps://doi.org/10.1093/nar/gkaf954
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