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October 3, 2025Journal of Public Health and PharmacyOpen Access

Efficacy and Safety of Cannabidiol for Anxiety: A Bibliometric Analysis and Systematic Review

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Authors

PFPutu Ayu Putri FajaryaniIWI Made Agus Gelgel WirasutaPSPande Made Nova Armita Sari

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Overview

Systematic review evaluates cannabidiol's efficacy and safety in anxiety, suggesting its potential benefits.

Key Points

  • Cannabidiol showed significant potential as an anxiolytic agent in treating anxiety disorders, indicating its efficacy.
  • A dosage of 300 mg/day in humans was effective, while animal models showed a range of 5 – 10 mg/kg for anxiolytic effects.
  • The review included a total of 64 articles, providing a comprehensive overview of cannabidiol's effects and safety.
  • Although cannabidiol appears safer than diazepam in the short term, further studies are necessary to assess its long-term safety.

Cite This Study

Fajaryani et al. (2025) studied this question.

synapsesocial.com/papers/68e034fdf0e39f13e7fa33e5https://doi.org/10.56338/jphp.v5i3.6807
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cannabidiol in the treatment of anxiety disorders: a narrative review2025
  2. 2Effects of cannabidiol on anxiety- and depressive-like behaviors and cognition: a systematic review and meta-analysis of preclinical studies2026
  3. 3Effectiveness and safety of cannabis on anxiety treatment outcomes: a systematic review2026
  4. 4Integrating Cannabidiol into Adolescent Psychiatry: Clinical Applications and Safety-Risk Profile for Treatment of Anxiety, Depression, and Post-traumatic Stress Disorder2026
  5. 5Clinical and Cognitive Improvement Following Treatment with a Hemp-Derived, Full-Spectrum, High-Cannabidiol Product in Patients with Anxiety: An Open-Label Pilot Study2025