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October 3, 2025Jurnal KesehatanOpen Access

Comparison of DNA Extraction Feasibility from Menstrual Blood and Endometrial Tissue in Reproductive-Aged Women

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Authors

FFebriyeniAHAndon HestiantoroAAAsmarinah Asmarinah

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Overview

This analysis shows no difference in DNA purity in menstrual blood and endometrial tissue, indicating reliable extraction methods.

Key Points

  • Menstrual blood and endometrial tissue both yield DNA with high purity and concentration.
  • Average DNA concentration was significantly higher in endometrial tissue at 192 ng/µL compared to 116.9 ng/µL for menstrual blood.
  • DNA extraction utilized QIAamp DNA Mini Kit for menstrual blood and Geneaid DNA Isolation Kit for tissue samples.
  • Results suggest menstrual blood can be as effective as endometrial tissue for DNA extraction, supporting its use in research.

Cite This Study

Febriyeni et al. (2025) studied this question.

synapsesocial.com/papers/68e03505f0e39f13e7fa3b60https://doi.org/10.35730/jk.v16i2.1314
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Single-nucleus analysis of menstrual fluid highlights gene expression differences in epithelial cells of endometriosis donors2026
  2. 2O-268 Re-considering the endometrial microbiome: a comparison of DNA- and RNA-based sequencing techniques within the same cohort2024
  3. 3Microbiological Profiling of Menstrual Blood Aspirated from the Uterus in Patients Undergoing Frozen Embryo Transfer2026
  4. 4Identification of menstrual blood markers by proteomic mass spectrometry2025
  5. 5Cell type profile variation in menstrual effluent by sample collection method identified using methylation cytometry2024