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October 3, 2025Clinical ChemistryOpen Access

A-406 Lactate at the SGH Emergency Department – can Point-of-Care Test Results be Interpretated Interchangeably with Central Laboratory Test Results?

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Poor agreement was found between lactate measurements from the Cobas b221 and the Beckman Coulter AU5800, implying they cannot be interchanged.
Using the i-STAT Alinity showed better correlation with both Cobas b221 and Beckman AU5800, demonstrating its reliability in emergency care.
Method comparison involved 91 patient samples, emphasizing the importance of accurate lactate measurements for clinical decision-making.
The study calls for careful communication to clinicians regarding the interchangeability of lactate test results from different platforms.

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Observational analysis reveals poor agreement between point-of-care and central laboratory lactate results, suggesting caution in interpretation.

Tan et al. (2025) studied this question.

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Observational analysis reveals poor agreement between point-of-care and central laboratory lactate results, suggesting caution in interpretation.