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October 3, 2025Clinical ChemistryOpen Access

A-254 Molecular characterization of carbapenem and colistin resistance in isolates causing UTI at an outpatient setting of a tertiary care hospital

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Authors

CMChandan MishraAll India Institute of Medical SciencesSMSuneeta MeenaAll India Institute of Medical SciencesPMPurva MathurAll India Institute of Medical Sciences

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Implication

Observational study determined carbapenem and colistin resistance in urinary infections, indicating significant alerts for outpatient antibiotic management.

Key Points

  • Colistin resistance in Carbapenem Resistant Enterobacterales was found to be 11%, highlighting a significant concern.
  • A total of 669 urine specimens were significant, with 9.79% yielding growth, indicating the prevalence of infections.
  • This prospective observational study focused on outpatient settings, revealing lower resistance patterns compared to inpatient studies.
  • Presence of resistance genes like blaNDM and blaOXA-48 raises alarms for infection control in outpatient environments.

Cite This Study

Mishra et al. (2025) studied this question.

synapsesocial.com/papers/68e040eda99c246f578b323ehttps://doi.org/10.1093/clinchem/hvaf086.243
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Colistin Susceptibility among Multidrug-Resistant Gram- Negative Pathogens isolated from Blood Culture: Evidence from a Tertiary Care Setting in Delhi, India2025
  2. 2Molecular characterization of blaNDM and other carbapenemases genes among carbapenem-resistant Enterobacterales from community-and hospital- acquired urinary tract infections2025 · 2 citations
  3. 3Prevalence of ESBL Producing and Carbapenem-resistant E. Coli in Urinary Tract Infection from Tertiary Care Hospital2025
  4. 4Phenotypic characterisation and prevalence of carbapenem-resistant Enterobacterales in a tertiary care centre in Bihar India2025 · 6 citations
  5. 5Detection of antibiogram pattern and prevalence of blaNDM and blaVIM genes among carbapenem resistant Eschericia coli isolates in a tertiary care hospital2024