What type of study is this?

This is a Quantitative Study study.

LC-MS/MS Method for Simultaneous Quantification of Three Oxazolidinone Antimicrobials in Human Plasma: Application to Therapeutic Drug Monitoring

View Full Paper

Ask AI

Bookmark

Authors

Method demonstrates accurate quantification of oxazolidinone drugs in plasma, highlighting its suitability for therapeutic drug monitoring.

The method enables accurate simultaneous quantification of oxazolidinone antimicrobials in plasma, supporting better patient care.
Validation showed high selectivity, with linear ranges reaching up to 15,000 ng/mL for linezolid and contezolid, and 7500 ng/mL for tedizolid.
Detective methods included positive ESI+ in multiple reaction monitoring mode, ensuring robust detection of all targeted drugs.
Stability tests confirmed analyte integrity, with negligible matrix effects and no carry-over contamination in the analytic process.

Zhang et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Method demonstrates accurate quantification of oxazolidinone drugs in plasma, highlighting its suitability for therapeutic drug monitoring.