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October 5, 2025Clinical review for general practiceOpen Access

Evaluation of cardiac magnetic resonance imaging parameters in cancer patients receiving chekpoint-inhibitor therapy

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Authors

УХУ. В. ХарламоваАВА. В. ВаженинOKOlga V. Kurchenkova

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Overview

Prospective evaluation reveals left ventricular changes in cancer patients on checkpoint-inhibitor therapy, indicating cardiac complications.

Key Points

  • Cardiac MRI revealed structural changes in the myocardium of 3 patients (18.75%) on checkpoint inhibitors.
  • A significant decrease in left ventricular ejection fraction (p=0.001) and an increase in end-diastolic volumes (p=0.004) were observed.
  • The study involved 85 cancer patients over three months, using the H2FPEF and SACCHF scales for assessment.
  • Findings highlight the importance of monitoring heart function in cancer patients receiving immune therapy.

Cite This Study

Харламова et al. (2025) studied this question.

synapsesocial.com/papers/68e24e60d6d66a53c247325dhttps://doi.org/10.47407/kr2025.6.7.00640
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