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October 5, 2025Clinical review for general practiceOpen Access

Pathogenetic factors of vaginal atrophy

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Authors

МОМ.Р. ОразовVRViktor E. RadzinskyЛМЛ.М. Михалева

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Overview

Prospective study shows changes in vaginal tissue markers vimentin and desmin in atrophic vaginitis, suggesting underlying pathogenesis.

Key Points

  • Significant changes in vaginal wall remodeling markers indicate a link to atrophic vaginitis.
  • Vimentin levels decreased by 1.68 times and desmin by 2.28 times in atrophic vaginitis compared to controls.
  • The study involved postmenopausal women diagnosed with atrophic vaginitis and a control group.
  • Findings highlight the importance of understanding connective tissue dynamics in vaginal health.

Cite This Study

Оразов et al. (2025) studied this question.

synapsesocial.com/papers/68e24e60d6d66a53c2473260https://doi.org/10.47407/kr2025.6.7.00651
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