Neuroendocrine tumors of the stomach and H. pylori infection: features of patient monitoring on the example of a clinical case

n this clinical case, we present an observation of a 36-year-old patient with a highly differentiated neuroendocrine tumor (NEO) of the stomach (NET G2, Ki-67.7%), which developed against the background of autoimmune gastritis and persistent infection with Helicobacter pylori (H. pylori). Despite the absence of detection of H. pylori during histological examination, the infection was confirmed by the determination of the H. pylori antigen in feces by enzyme immunoassay (ELISA), which confirms the need for a comprehensive diagnosis of the pathogen in this category of patients. The clinical case demonstrates the relationship between autoimmune gastritis, H. pylori infection and the development of NEO, and also confirms the effectiveness of a multidisciplinary approach in the treatment of such clinical situations.