Table 1 from Late-Stage Outcomes as Surrogates for Mortality in Cancer Screening Trials: A Systematic Review and Meta-analysis

This is a Systematic Review study (also classified as: Meta-Analysis).

October 3, 2025Open Access

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Key Points

The analysis reveals late-stage outcomes can predict mortality in cancer screening trials, potentially guiding clinical strategies.
Out of 57 trials included, findings suggest mortality surrogates are essential for evaluating cancer screening effectiveness.
This systematic review and meta-analysis integrates diverse trial data to enhance understanding of cancer outcomes.
Understanding these surrogates could significantly impact cancer prevention programs and health policy formulation.

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Systematic review and meta-analysis evaluates mortality surrogates in cancer screening trials, suggesting key insights.

Summary of the design and other characteristics of the 57 trials included in the systematic review and meta-analysis.

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Rebolj et al. (2025) studied this question.

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