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October 5, 2025CureusOpen Access

Preoperative Prediction of Chronic Post-surgical Pain Risk After Total Knee Arthroplasty: Insights From a Single-Center Case-Control Study

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Authors

BSBhavesh SantaniAshford and St Peter's Hospitals NHS Foundation TrustSDSoumen Das DeRoyal Surrey County HospitalDVDiego Vergara-JalandoniAshford and St Peter's Hospitals NHS Foundation Trust

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Implication

Case-control study identifies predictors of chronic post-surgical pain in TKA patients, suggesting targeted interventions.

Key Points

  • Chronic post-surgical pain affected 15.7% of patients after total knee arthroplasty, highlighting a significant issue.
  • Patients with coronary artery disease had the strongest association with chronic pain, indicated by an odds ratio of 2.98.
  • Multivariate analysis refined a scoring system based on seven risk factors, enhancing predictive ability for chronic pain.
  • Identifying risk factors may lead to better patient stratification and targeted interventions, reducing chronic pain impacts.

Cite This Study

Santani et al. (2025) studied this question.

synapsesocial.com/papers/68e2537cd6d66a53c24743c5https://doi.org/10.7759/cureus.93815
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The neuropathic component in persistent postsurgical pain: A systematic literature review2012 · 485 citations
  2. 2What are the factors of residual pain after uncomplicated TKA?2011 · 193 citations
  3. 3From past to digital time: Bibliometric perspective of worldwide research productivity on robotic and computer-assisted arthroplasty2024 · 15 citations
  4. 4Prediction of persistent pain after total knee replacement for osteoarthritis2008 · 276 citations
  5. 5Evaluation of patients with a painful total knee replacement2008 · 153 citations