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January 1, 2022BioMed Research InternationalOpen Access

Each year of preoperative pain linked to ~27% greater risk of persistent pain 6 months post-TKA.

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Why the study?

A significant number of patients complain of persistent pain of unknown origin after total knee arthroplasty, and identifying preoperative chronic pain predictors could enable proper education and realistic expectations.

What are the preoperative risk factors for persistent pain following total knee arthroplasty?

Population

64 patients scheduled for total knee arthroplasty

Comparison

Patients with no pain vs patients with any pain post-surgery

Design

Prospective cohort study

Follow-up

Approximately 6 months

Key result

Every 12 months of preoperative pain increased the risk of persistent pain 6 months following total knee arthroplasty by a factor of 1.27 (p=0.009).

Authors

PCPaweł ChodórJKJacek Kruczyński

Discussion

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Overview

Longer preoperative pain duration associated with post-TKA persistent pain; hypothesis-generating and should not yet change surgical timing.

Study Design

Type

Cohort (n=64)

Structured PICO

What are the preoperative risk factors for persistent pain following total knee arthroplasty?

P
Population
64 patients (mean age 67.6 years, 76.6% female) scheduled for total knee arthroplasty, evaluated approximately 6 months following surgery.
E
Exposure
Total knee arthroplasty (TKA)
O
Outcome
Persistent pain at approximately 6 months following surgerypatient reported

Main Result

Relative Risk: 1.27

p-value: p=0.009

Longer duration of preoperative pain is a significant risk factor for persistent chronic pain following total knee arthroplasty, suggesting surgical intervention should not be delayed.

Cite This Study

Chodór et al. (2022) conducted a cohort in Idiopathic osteoarthritis of the knee (n=64). Preoperative duration of pain vs. Shorter preoperative duration of pain was evaluated on Persistent pain at 6 months following surgery (Risk increase 1.27 per 12 months, p=0.009). Every 12 months of preoperative pain increased the risk of persistent pain 6 months following total knee arthroplasty by a factor of 1.27 (p=0.009).

synapsesocial.com/papers/6aa165771fe7c765783d445chttps://doi.org/10.1155/2022/4958089
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Predictors and Prevalence of Persistent Pain after Total Knee Arthroplasty in One-Year Follow-up2024 · 1 citations
  2. 2THE ROLE OF PREOPERATIVE FACTORS ON ACUTE POSTOPERATIVE PAIN AND PHYSICAL FUNCTION AFTER TOTAL KNEE ARTHROPLASTY2025 · 1 citations
  3. 3Are preoperative psychological factors associated with chronic postoperative pain after total knee arthroplasty: a systematic review2026
  4. 4Preoperative Prediction of Chronic Post-surgical Pain Risk After Total Knee Arthroplasty: Insights From a Single-Center Case-Control Study2025 · 1 citations
  5. 5The Impact of Acute Postoperative Pain in Developing Chronic Pain after Total Knee Arthroplasty2024 · 13 citations