Objective: This study aimed to assess the knowledge, attitudes, and practices (KAP) of operating room nurses regarding the prevention of MDRPIs and to identify factors influencing their KAP levels. Methods: A cross-sectional survey was conducted using a convenience sample of 108 nurses from hospitals in Guangdong Province. The survey included a KAP questionnaire developed by Hu Yu Ding, which measures knowledge, attitudes, and behavior related to MDRPI prevention. Data were analyzed using SPSS 22.0, with multivariate linear regression to identify influencing factors. Results: The total KAP score for preventing MDRPIs was (137.46±25.78) points, with knowledge scoring (46.35±13.24), attitudes (37.54±6.22), and behavior (53.57±12.01). Regression analysis identified hospital level and gender as significant predictors of KAP levels (all P<0.05). Notably, nurses in higher-level hospitals and female nurses demonstrated better KAP. Conclusion: While operating room nurses exhibited a positive attitude towards MDRPI prevention, there is a need to improve their knowledge and behavior. Training programs should be tailored to address these gaps, particularly focusing on nurses in lower-level hospitals and male nurses. Contribution: This study contributes to the body of knowledge by providing insights into the specific educational needs of operating room nurses for MDRPI prevention and suggesting targeted interventions to enhance patient safety and reduce healthcare-associated complications.
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