Objective: This study aimed to assess the current knowledge and training needs of operating room nurses regarding the prevention of MDRPIs. By identifying gaps in knowledge and influential factors, the study sought to provide a basis for targeted educational interventions to reduce the occurrence of these injuries. Methods: A convenient sampling method was employed to survey 108 nurses from five hospitals in Guangdong Province. Data was collected using a questionnaire that assessed nurses' knowledge and training needs related to MDRPI prevention. The questionnaire included sections on general information, knowledge assessment, and training demand. Statistical analysis was performed using SPSS 22.0, with multivariate linear regression to identify influential factors. Results: The mean knowledge score was 30.63 out of a possible 39, indicating a need for improvement. The mean training demand score was 45.23 out of 55, reflecting a high demand for training. Regression analysis identified hospital grade, gender, and age as significant factors influencing knowledge scores, while hospital grade and professional title were related to training demand. Conclusion: Operating room nurses demonstrate a moderate level of understanding regarding the prevention of medical devicerelated pressure injuries (MDRPIs), yet there is room for improvement. The high scores in training needs reflect a proactive learning attitude. Hospital grade, gender, age, and professional title are identified as the primary factors influencing knowledge scores and training demands.
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