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September 26, 2024

Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation

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Authors

FNFrancisco NealThe University of Texas Health Science Center at San AntonioWLWenjing LiThe University of Texas Health Science Center at San AntonioMUMollie E. UhrigColorado State University

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Neal et al. (2024) studied this question.

synapsesocial.com/papers/68e5752db6db643587514e39https://doi.org/10.1101/2024.09.24.614752
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Also Consider

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  1. 1DSS1 restrains BRCA2’s engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis2024 · 13 citations
  2. 2In situ click chemistry generation of cyclooxygenase-2 inhibitors2017 · 7,560 citations
  3. 3The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange2009 · 75 citations