This report describes a novel case of urethral adenocarcinoma in situ with enteric (gastric-type) differentiation in a 74-year-old female presenting with recurrent urinary tract infections and obstructive urinary symptoms. Magnetic resonance imaging (MRI) revealed a urethral diverticulum (UD), and a diverticulectomy was performed. Pathology from samples obtained during this operation revealed this rare subtype of malignancy. Our case highlights the importance of considering a broad differential diagnosis, even in patients with atypical presentations, and the need for further research to optimize the detection and treatment of this disease.
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Johnson et al. (2024) studied this question.
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